Anti-VEGFA Antibody, EP1176Y

Also for VEGFA (NM_001025368)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues on the C-terminus of human VEGF was used as an immunogen.
Clone Name	EP1176Y	Isotype	Rabbit IgG
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:1000; IHC: 1:50 100; ICC: 1:250 500; FC: 1:25; IP: 1:50
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 4
Alternative Name	MGC70609; MVCD1; VEGF; VPF
Database Link	NP_001020539
Function	This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq].
Related Pathway	Cytokine-cytokine receptor interaction Focal Adhesion Hemostasis

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WB Image

Western blot analysis on 5 ng of recombinant protein using anti-VEGF RabMAb (TA303731), dilution 1:1000.

IHC Image

Immunohistochemical staining of hemangioma using anti-VEGF RabMAb (TA303731).

IF Image

Immunofluorescent staining of HUVEC cells using anti-VEGF RabMAb (TA303731).

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Anti-VEGFA Antibody EP1176Y

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data