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Anti-VEGFA Antibody EP1176Y
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Also for VEGFA (NM_001025368)
|A synthetic peptide corresponding to residues on the C-terminus of human VEGF was used as an immunogen.|
|WB, IHC, IF
||WB: 1:1000; IHC: 1:50 100; ICC: 1:250 500; FC: 1:25; IP: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 4|
|MGC70609; MVCD1; VEGF; VPF|
|This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq]. |
Cytokine-cytokine receptor interaction
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Western blot analysis on 5 ng of recombinant protein using anti-VEGF RabMAb (TA303731), dilution 1:1000.
Immunohistochemical staining of hemangioma using anti-VEGF RabMAb (TA303731).
Immunofluorescent staining of HUVEC cells using anti-VEGF RabMAb (TA303731).