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Anti-VAV3 Antibody EP1130Y
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Also for VAV3 (NM_001079874)
|A synthetic peptide corresponding to residues near the C-term of human Vav3 was used as an immunogen.|
||WB: 1:100,000; FC: 1:40; IP: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2|
|This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]. |
EGFR1 Signaling Pathway
Signaling by GPCR
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Western blot analysis on Jurket cell lysate using anti-Vav3 RabMAb (TA303772), dilution 1:100,000
Flow cytometric analysis of permeabilized Jurkat cells using anti-VAV3 pan RabMAb (red) (TA303772) or a rabbit IgG (negative) (green).