Home Antibody All anti-VAV3 antibodies
Also for VAV3 (NM_001079874)
| Peptide with sequence CSGEQGTLKLPEK, from the internal region of the protein sequence according to NP_006104.4; NP_001073343.1.|
|Test: Human. Expected from seq similarity: Human, Dog
||ELISA: 1:128,000. WB: 0.3-1µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2|
Entrez Gene 10451 Human
Entrez Gene 479921 Dog
|This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]. |
EGFR1 Signaling Pathway
Signaling by GPCR
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TA302958 (0.3µg/ml) staining of human bone marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.