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Anti-VAV2 Antibody EP1067Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303730 Rabbit monoclonal antibody against Vav 2 (EP1067Y ) 100ul $325 In Stock
LC418726 VAV2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on human Vav2 was used as an immunogen. This antibody detects Vav2 phosphorylated on Tyr172 as well as unphosphorylated Vav2.
Clone NameEP1067Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IP Suggested DilutionsWB: 1:20000; IP: Use at an assay dependent concentration; ICC: 1:100 - 1:250; IHC-P: Use at an assay dependent dilution
Predicted MW Explanation 101 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens vav guanine nucleotide exchange factor 2 (VAV2), transcript variant 2
Alternative NameVAV-2
Database LinkNP_003362
Entrez Gene 7410 Human
Entrez Gene 22325 Mouse
Entrez Gene 296603 Rat
FunctionVAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Chemokine signaling pathwayFocal adhesionNatural killer cell mediated cytotoxicityT cell receptor signaling pathwayB cell receptor signaling pathwayFc epsilon RI signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - VAV2 antibody [EP1067Y]; Anti-VAV2 antibody [EP1067Y] at 1/20000 dilution + 293 cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP labeled at 1/2000 dilution.Predicted band size : 101 kDa.Observed band size : 101 kDa.

IHC Image
Immunohistochemistry (Paraffin-embedded sections) - VAV2 antibody [EP1067Y]; Human cervical carcinoma stained with TA303730 at 1/50 - 1/100 dilution

IP Image
VAV2 was immunoprecipitated using 0.5mg Hek293 whole cell extract, 10ug of Rabbit monoclonal to VAV2 and 50ul of protein G magnetic beads (+). No antibody was added to the control (-). Secondary Antibody to Rabbit IgG light chain (HRP) .Band: 100kDa; VAV2.


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