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Anti-USP39 Antibody EPR8684
Also for USP39 (NM_006590)
|A synthetic peptide corresponding to residues on the C-terminus in human USP39 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||ICC/IF: 1:250 - 1:500; WB: 1:10000 - 1:50000; IHC-P: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens ubiquitin specific peptidase 39 (USP39), transcript variant 1|
|65K; CGI-21; HSPC332; SAD1; SNRNP65|
Entrez Gene 10713 Human
Entrez Gene 28035 Mouse
Entrez Gene 297336 Rat
|USP39 (U4/U6.U5 tri-snRNP-associated protein 2) is involved in the assembly of the spliceosome, the RNA splicing machinery. The spliceosome consists of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5 and U6 as well as a large number of non-snRNP proteins. It is essential for the recruitment of tri-snRNP to the pre-spliceosome and is known as a tri-snRNP-specific protein. USP39 is also a deubiquitinating enzyme, but it lacks protease activity due to absence of key active-site residues cysteine and histidine (1).|
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Western blot - Anti-USP39 antibody [EPR8684]; All lanes : Anti-USP39 antibody [EPR8684] at 1/10000 dilution.Lane 1 : 293T cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 65 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP39 antibody [EPR8684]; Immunohistochemical analysis of paraffin-embedded Human colon tissue labelling USP39 with TA310937 at 1/50 dilution.
Immunocytochemistry/ Immunofluorescence - Anti-USP39 antibody [EPR8684]; Immunofluorescent analysis of HeLa cells labelling USP39 with TA310937 at 1/250 dilution.