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Anti-UNG TRUEMAB Antibody clone 2C12
TrueMAB Antibodies - Made against Authentic Protein Antigens
|Full length human recombinant protein of human UNG(NP_550433) produced in HEK293T cell.|
|WB, IHC, IF
||WB 1:500~2000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens uracil-DNA glycosylase (UNG), transcript variant 2|
|DGU; HIGM4; HIGM5; UDG; UNG1; UNG15; UNG2|
Entrez Gene 7374 Human
|This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq].|
|Stem cell - PluripotencyDruggable Genome Base excision repairPrimary immunodeficiency|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UNG (RC222868, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UNG.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-UNG monoclonal antibody.
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503563)
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503563)
Anti-UNG mouse monoclonal antibody (TA503563) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY UNG(RC222868).