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Home Antibody All anti-UNC13D antibodies

Anti-UNC13D Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305698
  • Goat Anti-Munc13-4 / UNC13D (C terminus) Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403710) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for UNC13D (NM_199242)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-KQASQHALRPAP, from the C Terminus of the protein sequence according to NP_954712.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens unc-13 homolog D (C. elegans) (UNC13D)
Alternative NameFHL3; HLH3; HPLH3; Munc13-4
Database LinkNP_954712
FunctionThis gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq].
Related Pathway

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WB Image
TA305698 (2ug/ml) staining of Human T-lymphocyte lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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