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Home Antibody All anti-UNC13B antibodies

Anti-UNC13B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308990
  • Rabbit Polyclonal antibody to UNC13B (unc-13 homolog B (C. elegans))
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 927 of human UNC13B
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens unc-13 homolog B (C. elegans) (UNC13B)
Alternative NameMUNC13; UNC13; Unc13h2
Database LinkNP_006368
FunctionThis gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate) A: 293T (anti-UNC13B antibody diluted at 1:500)
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using UNC13B(anti-UNC13B antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using UNC13B(anti-UNC13B antibody) antibody at 1:200 dilution.

 

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