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Home Antibody UltraMAB

UltraMAB

AMACR UltraMAB Antibody, Clone UMAB68

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (0) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM800012
  • AMACR mouse monoclonal antibody,clone UMAB68, 100 ul
$468 In Stock Add to Shopping Cart
UM870012
  • AMACR mouse monoclonal antibody,clone UMAB68, 30 ul
$120 In Stock Add to Shopping Cart
IHC(2)
Data Img
IF(1)
Data Img
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Also for AMACR (NM_014324)
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OriGene Data

ImmunogenFull length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.
Clone NameClone UMAB68 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC, IF Suggested Dilutions IHC 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1
Alternative NameAMACRD; CBAS4; RACE; RM
Database LinkNP_055139
FunctionThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-AMACR mouse monoclonal antibody. (UM800012; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded of human kidney using anti-AMACR clone UMAB68 mouse monoclonal antibody at 1:200 dilution of 1.0mg/mL using Polink2 Broad HRP DAB detection kit. UM800012 requires heat-induced epitope retrieval with Citrate pH6.0 in a pressure chamber/cooker high 3min. The image shows strong cytoplsamic staining in the kidney tubual cells.
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Immunofluorescent staining of HeLa cells using anti-AMACR mouse monoclonal antibody (UM800012, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue).
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