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UltraMAB

GBA UltraMAB Antibody, Clone UMAB171

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (0) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM800064
  • GBA mouse monoclonal antibody,clone UMAB171, 100 ul
$379 In Stock Add to Shopping Cart
UM870064
  • GBA mouse monoclonal antibody,clone UMAB171, 30 ul
$120 In Stock Add to Shopping Cart
IHC(10)
Data Img
IF(1)
Data Img
10K-CHIP(1)
Data Img

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Clone NameClone UMAB171 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC, IF, 10K-CHIP Suggested Dilutions IHC 1:100~200,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glucosidase, beta, acid (GBA), transcript variant 1
Alternative NameGBA1; GCB; GLUC
Database LinkNP_000148
FunctionThis gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
Related Pathway

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Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-GBA mouse monoclonal antibody. (UM800064; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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Immunofluorescent staining of MCF-7 cells using anti-GBA mouse monoclonal antibody (UM800064, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue).
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OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-GBA mouse monoclonal antibody (UM800064). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
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