A PKG inhibitor increases Ca2+-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition Am J Physiol Gastrointest Liver Physiol, May 2013; 304: G773 - G780.
[PDE2A]
Lck tyrosine kinase mediates ß1-integrin signalling to regulate Schwann cell migration and myelination Nature Communications 4, 1912 doi:10.1038/ncomms2928
[OCT6]
Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours J. Clin. Pathol., May 2013; 66: 386 - 391.
[Notch 1]
Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis J. Leukoc. Biol., May 2013; 93: 771 - 780.
[anti-DDK]
UltraMAB™ Antibodies - Validated with 10K Protein Chip
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-TP63 mouse monoclonal antibody. (UM800026)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-$TP63mouse monoclonal antibody. (UM800026)
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-TP63 mouse monoclonal antibody. (UM800026)
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-TP63 mouse monoclonal antibody (UM800026). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].
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OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-TP63 mouse monoclonal antibody (UM800026). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
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