A PKG inhibitor increases Ca2+-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition Am J Physiol Gastrointest Liver Physiol, May 2013; 304: G773 - G780.
[PDE2A]
Lck tyrosine kinase mediates ß1-integrin signalling to regulate Schwann cell migration and myelination Nature Communications 4, 1912 doi:10.1038/ncomms2928
[OCT6]
Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours J. Clin. Pathol., May 2013; 66: 386 - 391.
[Notch 1]
Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis J. Leukoc. Biol., May 2013; 93: 771 - 780.
[anti-DDK]
UltraMAB™ Antibodies - Validated with 10K Protein Chip
Immunohistochemical staining of paraffin-embedded Human normal breast tissue and breast adenocarcinoma tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal colon tissue and colorectal cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal lung tissue and lung adenocarcinoma tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal pancreas tissue and pancreatic cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal bladder tissue and bladder cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-MUC1 mouse monoclonal antibody (Clone UMAB37). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-MUC1 (Clone UMAB57
) very specifically recognizes MUC1 antigen on OriGene protein microarray chip.
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].
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Immunohistochemical staining of paraffin-embedded Human normal breast tissue and breast adenocarcinoma tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal colon tissue and colorectal cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal lung tissue and lung adenocarcinoma tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal pancreas tissue and pancreatic cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
Immunohistochemical staining of paraffin-embedded Human normal bladder tissue and bladder cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-MUC1 mouse monoclonal antibody (Clone UMAB37). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-MUC1 (Clone UMAB57
) very specifically recognizes MUC1 antigen on OriGene protein microarray chip.
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