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CD1C UltraMAB Antibody, Clone UMAB46
UltraMAB Antibodies - Validated with 10K Protein Chip
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Also for CD1C (NM_001765)
|Full length human recombinant protein of human CD1C(NP_001756) produced in HEK293T cell.|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, 10K-CHIP
|| IHC 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens CD1c molecule (CD1C)|
|BDCA1; CD1; CD1A; R7|
|This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul |
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Western Blot analysis of MOLT-4 cell lysate (35µg) by using anti-CD1C monoclonal antibody (Clone UMAB46)
Immunohistochemical staining of paraffin-embedded human tonsil with mouse anti-CD1c clone UMAB46 1:200 dilution of 1mg/mL using HIER citrate pressure chamber. Shown here is a composit of 10x and 20x Imaging of tonsil with expression cytoplasmic and membraneous staining pattern.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CD1C mouse monoclonal antibody. (UM500042; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-CD1C mouse monoclonal antibody (UM500042). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.