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ALX4 UltraMAB Antibody, Clone Clone UMAB118

UltraMAB™ Antibodies - Validated with 10K Protein Chip


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SKU Description Datasheet Price Availability*  
  • ALX4 mouse monoclonal antibody,clone UMAB118, 100 ul
$468 In Stock Add to Shopping Cart
  • ALX4 mouse monoclonal antibody,clone UMAB118, 30 ul
$120 In Stock Add to Shopping Cart
  • Carrier-free (BSA/glycerol-free) ALX4 mouse monoclonal antibody,clone UMAB118
$528 3 days Add to Shopping Cart
Data Img
Data Img
Data Img

OriGene Data

ImmunogenFull length human recombinant protein of human ALX4(NP_068745) produced in HEK293T cell.
Clone NameClone Clone UMAB118 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *10K-CHIP, WB, IHC Suggested Dilutions IHC 1:100~200,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from cell culture supernatant by affinity chromatography

Reference Data

Target NameHomo sapiens ALX homeobox 4 (ALX4)
Alternative NameCRS5; FND2
Database LinkNP_068745
FunctionThis gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009].
Related Pathway

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OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-ALX4 mouse monoclonal antibody (UM500083). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
Western blot of cell lysates (35ug) from 8 different cell lines (1: HepG2, 2: HeLa, 3: SV-T2, 4: MCF7, 5: COS7, 6: Jurkat, 7: MDCK, 8: PC-12). Diluation: 1:500.
Immunohistochemical staining of FFPE human breast tissue section using anti-ALX4 mouse monoclonal antibody UM500083, clone UMAB118 at 1:200. (Heat-induced epitope retrieval by Tris-EDTA, pH9.0; Polink1 Broad HRP for 15 min; DAB chromogen for 5 min & DAB enhancer for 30 sec).


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