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UltraMAB

PBX1 UltraMAB Antibody, Clone UMAB110

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (0) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500077
  • PBX1 mouse monoclonal antibody,clone UMAB110, 100 ul
$468 In Stock Add to Shopping Cart
UM570077
  • PBX1 mouse monoclonal antibody,clone UMAB110, 30 ul
$120 In Stock Add to Shopping Cart
IHC(8)
Data Img
IF(1)
Data Img
10K-CHIP(1)
Data Img

OriGene Data

ImmunogenFull length human recombinant protein of human PBX1(NP_002576) produced in HEK293 cell.
Clone NameClone UMAB110 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC, IF, 10K-CHIP Suggested Dilutions IHC 1:100~200,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1
Alternative NameDKFZp686B09108; MGC126627
Database LinkNP_002576
FunctionThis gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar
Related Pathway

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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PBX1mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human tonsil using anti-PBX1 mouse monoclonal antibody. (UM500077; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunofluorescent staining of HeLa cells using anti-PBX1 mouse monoclonal antibody (UM500077, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue).
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OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-PBX1 mouse monoclonal antibody (UM500077). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
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