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OriGene Antibodies in recent publications

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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KRT18 UltraMAB Antibody, Clone UMAB50

UltraMAB™ Antibodies - Validated with 10K Protein Chip

Specifications

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Conjugation/Bulk

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SKU	Description	Datasheet	Price	Availability*
UM500045	Purified KRT18 mouse monoclonal antibody, clone UMAB50, 100 ul		$468 *	In Stock
UM570045	Purified KRT18 mouse monoclonal antibody, clone UMAB50, 30 ul		$120	In Stock

IHC(18)

Also for KRT18 (NM_199187)

Protein Request

Gene Name	Homo sapiens keratin 18 (KRT18), transcript variant 2
Synonyms	CYK18; K18
Immunogen	Human recombinant protein fragment corresponding to amino acids 69-372 of human KRT18 (NP_000215) produced in E.coli.
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Name	Clone UMAB50	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *	IHC	Suggested Dilutions	IHC 1:100,
Background	KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul

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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KRT18 mouse monoclonal antibody. (UM500045)

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