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UltraMAB

MEF2C UltraMAB Antibody, Clone UMAB17

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations Customer Reviews Product Documents
SKU Description Datasheet Price Availability*  
UM500017
  • MEF2C mouse monoclonal antibody,clone UMAB17, 100 ul
$468 In Stock Add to Shopping Cart
UM570017
  • MEF2C mouse monoclonal antibody,clone UMAB17, 30 ul
$120 In Stock Add to Shopping Cart
IHC(4)
Data Img
IF(2)
Data Img
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OriGene Data

ImmunogenFull length human recombinant protein of human MEF2C(NP_002388) produced in HEK293T cell.
Clone NameClone UMAB17 IsotypeIgG2b
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC, IF Suggested DilutionsWB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1
Alternative NameC5DELq14.3; DEL5q14.3
Database LinkNP_002388
FunctionThis locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Immunohistochemical staining of paraffin-embedded human tonsil using anti-MEFC2 clone UMAB17 mouse monoclonal antibody at 1:200 with Polink2 Broad HRP DAB detection kit (UM500017); heat-induced epitope retrieval with citrate buffer, pH6.0 at 95-100C. Nuclear staining seen in both the germinal and non germinal centers of the the tonsil
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Immunohistochemical staining of paraffin-embedded human melanoma using anti-MEFC2 clone UMAB17 mouse monoclonal antibody at 1:200 with Polink2 Broad HRP DAB detection kit (UM500017); heat-induced epitope retrieval with citrate buffer, pH6.0 at 95-100C. Nuclear staining seen in the infiltrating lymphocyte and weak staining in tumor cells.
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Immunohistochemical staining of paraffin-embedded Human embryonic brain tissue using anti-MEF2C mouse monoclonal antibody. (Clone UMAB17; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MEF2C mouse monoclonal antibody. (Clone UMAB17; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Confocal immunofluoresce image of primary rat neurons labeled with anti-MEF2C mouse monoclonal antibody (UM500017, green, 1:50) and with DAPI (blue) for nuclear. Scale bar, 10µm.
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Immunofluorescent staining of SH-SY5Y cells using anti-MEF2C mouse monoclonal antibody (UM500017, green, 1:100). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue). Scale bar, 20µm.
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