OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
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ERCC1 UltraMAB Antibody, Clone 4F9
UltraMAB™ Antibodies - Validated with 10K Protein Chip
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ERCC1 monoclonal antibody (Clone 4F9).
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded lung tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded thyroid tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of endometrium tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded bladder tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
Immunofluorescent staining of HeLa cells using anti-ERCC1 mouse monoclonal antibody (UM500008, Clone 4F9).
Also for ERCC1 (NM_001983)
Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), transcript variant 2 COFS4; RAD10; UV20 Protein expressed in 293T cell transfected with human ERCC1 expression vector PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone 4F9
IgG1
Human
0.5~1.0 mg/ml (Lot Dependent)
Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose )
WB, IHC, IF
WB 1:2000, IHC 1:50, IF 1:100,
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
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WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ERCC1 monoclonal antibody (Clone 4F9).
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded lung tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded thyroid tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of endometrium tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded bladder tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-ERCC1 mouse monoclonal antibody. (Clone 4F9, Dilution 1:50)
IF Image
Immunofluorescent staining of HeLa cells using anti-ERCC1 mouse monoclonal antibody (UM500008, Clone 4F9).
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