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Home Antibody All anti-ULK3 antibodies

Anti-ULK3 Antibody EPR4888

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310926
  • Rabbit Monoclonal antibody against ULK3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC420458) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ULK3 (NM_001099436)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human ULK3 was used as an immunogen.
Clone NameEPR4888 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:25 - 1:50; FC: 1:10 - 1:100; IHC-P: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens unc-51 like kinase 3 (ULK3), transcript variant 1
Alternative NameDKFZp434C131; FLJ90566
Database LinkNP_001092906
FunctionULK3 is a serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. It may exert this function by promoting GLI1 nuclear localization. ULK3 phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently (1).
Related Pathway

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WB Image
Western blot - Anti-ULK3 antibody [EPR4888]; All lanes : Anti-ULK3 antibody [EPR4888] at 1/1000 dilution.Lane 1 : Human heart lysate.Lane 2 : Human testis lysate.Lane 3 : Human fetal kidney lysate.Lane 4 : LnCaP cell lysate.Lane 5 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ULK3 antibody [EPR4888]; TA310926, at a 1/50 dilution, staining ULK3 in paraffin embedded Human bladder carcinoma tissue by Immunohistochemistry.

 

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