Home Antibody All anti-UHRF1BP1 antibodies
Anti-UHRF1BP1 Antibody Polyclonal
Also for UHRF1BP1 (NM_017754)
|UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1.|
||ELISA, WB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|UHRF1BP1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|UHRF1BP1 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens UHRF1 binding protein 1 (UHRF1BP1)|
|C6orf107; dJ349A12.1; ICBP90; RP3-349A12.1|
|UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.|
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Western blot analysis of UHRF1BP1 in mouse kidney tissue lysate with UHRF1BP1 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of UHRF1BP1 in human kidney tissue with UHRF1BP1 antibody at 2.5 ug/mL.