Home Antibody All anti-UCHL1 antibodies
Also for UCHL1 (NM_004181)
|A synthetic peptide made to an internal portion of the human UCHL1 protein sequence (between residues 100-200). UniProt P09936|
|WB, IHC, IF
||WB: 0.5-2 ug/ml
|Tris-glycine and 150mM NaCl and 0.05% Sodium azide|
|Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)|
|HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1|
Entrez Gene 7345 Human
Entrez Gene 22223 Mouse
|UCHL1 is a soluble cytoplasmic protein with a molecular weight of approximately 25,000 kD. It is present in neurons and in cells of the diffuse neuroendocrine system. UCHL1 functions as a tissue-specific ubiquitin carboxyl terminal hydrolase isoenzyme. This enzyme is also known as PGP9.5. Because of its abundance in nerves, it has been widely used as a marker for peripheral nerve fibers.|
|ProteaseDruggable Genome Parkinson's disease|
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Detection of UCHL1 in mouse brain lysate. ECL detection, 60 seconds.
Staining of neurons and their cell processes with anti-PGP9.5 at 2.5ug/ml. Human brain, Substantia Nigra, Pigmented Neuron, 40X.
Immunocytochemistry/Immunofluorescence: UCHL1 antibody was tested in Neuro2a cells with FITC (green). Nuclei were counterstained with Dapi (blue).