Home Antibody All anti-UBQLN1 antibodies
Also for UBQLN1 (NM_053067)
|Recombinant fragment corresponding to a region within amino acids 64 and 345 of Ubiquilin-1 (Uniprot ID#Q9UMX0)|
|Human (Predicted: Mouse, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (90%), Rat (90%), Bovine (95%)
|Homo sapiens ubiquilin 1 (UBQLN1), transcript variant 2|
|DA41; DSK2; PLIC-1; UBQN; XDRP1|
Entrez Gene 29979 Human
Entrez Gene 56085 Mouse
Entrez Gene 114590 Rat
|This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308768 diluted at 1:1000.
Immunofluorescence analysis of paraformaldehyde-fixed A549, using Ubiquilin-1(TA308768) antibody at 1:200 dilution.