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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-UBE4B antibodies

Anti-UBE4B Antibody EPR7471

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310915
  • Rabbit Monoclonal antibody against UBE4B
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
Gene NameHomo sapiens ubiquitination factor E4B (UBE4B), transcript variant 1
Synonyms:E4; HDNB1; UBOX3; UFD2; UFD2A
ImmunogenA synthetic peptide corresponding to residues in human UBE4B was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR7471 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000 - 10,000;
BackgroundThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. It is also the strongest candidate in the neuroblastoma tumor suppressor (1).
Related Pathway

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WB Image
Western blot analysis on (A) 293T, (B) Raji, (C) SK-OV-3, (D) L929, (E) L6, (F) RAW 264.7, (G) PC-12, (H) NIH/3T3, (I) HeLa, and (J) K562 cell lysates using anti-UBE4B RabMAb.

 

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