Home Antibody All anti-UBE4B antibodies
Also for UBE4B (NM_001105562)
|Recombinant fragment corresponding to a region within amino acids 869 and 1179 of UBE4B (Uniprot ID#O95155)|
|Human (Predicted: Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Bovine (100%)
|Homo sapiens ubiquitination factor E4B (UBE4B), transcript variant 1|
|E4; HDNB1; UBOX3; UFD2; UFD2A|
Entrez Gene 10277 Human
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]|
| Ubiquitin mediated proteolysis|
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Sample (30 ug of whole cell lysate). A: Hep G2 . 5% SDS PAGE. TA308624 diluted at 1:10000
Immunohistochemical analysis of paraffin-embedded CA922 xenograft, using UBE4B(TA308624) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed Hep3B, using UBE4B(TA308624) antibody at 1:500 dilution.