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Home Antibody All anti-UBE3A antibodies

Anti-UBE3A Antibody EPR7330


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310913 Rabbit Monoclonal antibody against UBE3A 100ul $325 In Stock
LC400164 UBE3A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for UBE3A (NM_000462)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human UBE3A was used as an immunogen.
Clone NameEPR7330 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 100 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens ubiquitin protein ligase E3A (UBE3A), transcript variant 2
Alternative NameANCR; AS; E6-AP; EPVE6AP; HPVE6A
Database LinkNP_000453
Entrez Gene 7337 Human
Entrez Gene 22215 Mouse
Entrez Gene 361585 Rat
FunctionUBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted protein is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this protein causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53 (1).
Related PathwayDruggable Genome Ubiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-UBE3A antibody [EPR7330]; All lanes : Anti-UBE3A antibody [EPR7330] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 100 kDa.

Assay Image
Other-Anti-UBE3A antibody [EPR7330](TA310913); Equilibrium disassociation constant (KD)..


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