Home Antibody All anti-UBE2M antibodies
Anti-UBE2M TRUEMAB Antibody clone 2D9
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for UBE2M (NM_003969)
|Full length human recombinant protein of human UBE2M(NP_003960) produced in HEK293T cell.|
|Human , Dog , Monkey , Mouse
||WB 1:500~2000, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens ubiquitin-conjugating enzyme E2M (UBE2M)|
|hUbc12; UBC-RS2; UBC12|
Entrez Gene 9040 Human
Entrez Gene 22192 Mouse
Entrez Gene 712206 Monkey
Entrez Gene 484221 Dog
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq].|
| Ubiquitin mediated proteolysis|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UBE2M (RC208946, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBE2M.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-UBE2M monoclonal antibody.
Anti-UBE2M mouse monoclonal antibody (TA503770) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY UBE2M(RC208946).