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Anti-UBE2K Antibody EP1145Y
Also for UBE2K (NM_005339)
|A synthetic peptide corresponding to residues of human UBC1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5000; IHC: 1:250 500; ICC: 1:250; IP: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Homo sapiens ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1|
|E2-25K; HIP2; HYPG; LIG; UBC1|
Entrez Gene 3093 Human
Entrez Gene 53323 Mouse
Entrez Gene 289623 Rat
|The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]. |
|Transcription FactorsDruggable Genome Ubiquitin mediated proteolysis|
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Western blot - HIP2 antibody [EP1145Y]; Anti-HIP2 antibody [EP1145Y] at 1/100000 dilution + Daudi cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 22 kDa.Observed band size : 24 kDa .
Immunohistochemistry (Paraffin-embedded sections) - HIP2 antibody [EP1145Y]; Ab52930 (1:250) staining human HIP2 in human liver tissue by immunohistochemistry using paraffin embedded tissue.