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Home Antibody All anti-UBE2J2 antibodies

Anti-UBE2J2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319512
  • Rabbit polyclonal Ubiquitin-Conjugating Enzyme E2 J2 antibody
100ug 325 3-7 Days
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WB(1)
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Also for UBE2J2 (NM_058167)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the human Ube2j2 protein.
Clone Name IsotypeIgG
Species Reactivityhuman, mouse, rat Concentration0.91 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:5,000 - 1:25,000, WB: 1:500 - 1:3,000
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Ube2j2 and Ube2j1 are homologs of the yeast ubiquitin-conjugating enzyme UBC6, which catalyzes the covalent attachment of ubiquitin to other proteins. These proteins constitute a distinct family of ubiquitin-conjugating enzymes sharing a conserved non-canonical active site sequence and a C-terminal trans-membrane domain. By analogy with yeast UBC6, Ube2j1 and Ube2j2 are localized to the endoplasmic reticulum and seem to function in the selective degradation of misfolded membrane proteins and in general mediation of the stress response.

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2, J2 (UBE2J2), transcript variant 2
Alternative NameNCUBE-2; NCUBE2; PRO2121
Database LinkNP_477515
Entrez Gene 118424 Human
Entrez Gene 140499 Mouse
Entrez Gene 298689 Rat
Function
Related PathwayTransmembrane Ubiquitin mediated proteolysisParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot using affinity purified anti-Ube2j2 antibody shows detection of Ube2j2 in 293 cells over-expressing Myc-Ube2j2 (Lane 1). Lane 2 contains lysate from mock-transfected 293 cells. Personal Communication, A. Weissman & T. Shang, CCR-NCI, Frederick, MD

 

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