Home Antibody All anti-UBE2B antibodies
Also for UBE2B (NM_003337)
|Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 152 of UBE2B|
|Human, Mouse (Predicted: Rat, Pig, Rabbit, Rhesus Monkey, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rat (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%)
|Homo sapiens ubiquitin-conjugating enzyme E2B (UBE2B)|
|E2-17kDa; HHR6B; HR6B; RAD6B; UBC2|
Entrez Gene 7320 Human
Entrez Gene 22210 Mouse
Entrez Gene 81816 Rat
Entrez Gene 710678 Monkey
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq]|
|Druggable Genome Ubiquitin mediated proteolysis|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
UBE2B antibody detects UBE2B protein by western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug whole cell lysate/extract of 3xFlag-human UBE2B-transfected 293T cells. 12 % SDS-PAGE. UBE2B antibody (TA308525) dilution: 1:5000
Sample (30 ug of whole cell lysate). A: NIH-3T3 12% SDS PAGE. TA308525 diluted at 1:1000.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using UBE2B(TA308525) antibody at 1:500 dilution.