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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-TYMS antibodies

Anti-TYMS TrueMAB Antibody Clone 10F12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA801551
  • Purified TYMS mouse monoclonal antibody,clone 10F12
  • FREE positive control: HEK293T cell transient overexpression lysate (LC420700) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF801551
  • Carrier-free (BSA/glycerol-free) TYMS mouse monoclonal antibody,clone 10F12
100ug $450 8-10 Days Add to Shopping Cart
WB(1)
IHC(9)
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Also for TYMS (NM_001071)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens thymidylate synthetase (TYMS)
Synonyms:HST422; TMS; TS
ImmunogenFull length human recombinant protein of human TYMS (NP_001062) produced in E.coli.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 10F12 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BackgroundThymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq, Jul 2008].
Related Pathway
Cell cycle

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TYMS (RC204814, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TYMS.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-TYMS mouse monoclonal antibody. (TA801551)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-TYMS mouse monoclonal antibody. (TA801551)

 

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