OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-TYK2 antibodies

Anti-TYK2 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308735
  • Rabbit polyclonal antibody to TYK2 (tyrosine kinase 2)
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 680 and 1187 of TYK2 (Uniprot ID#P29597)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Pig, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 134kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (88%), Pig (88%), Bovine (87%)

Reference Data

Target NameHomo sapiens tyrosine kinase 2 (TYK2)
Alternative NameIMD35; JTK1
Database LinkNP_003322
Entrez Gene 7297 Human
Entrez Gene 54721 Mouse
FunctionThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]
Related PathwayProtein KinaseDruggable Genome Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:H1299. B:HeLa S3. 5% SDS PAGE. TA308735 diluted at 1:1000
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TYK2(TA308735) antibody at 1:200 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title