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Home Antibody All anti-TYK2 antibodies

Anti-TYK2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308735
  • Rabbit polyclonal antibody to TYK2 (tyrosine kinase 2)
100ul 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 1176 of TYK2
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens tyrosine kinase 2 (TYK2)
Alternative NameJTK1
Database LinkNP_003322
FunctionThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]
Related Pathway
Jak-STAT signaling pathway

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WB Image
Sample(30 ug whole cell lysate) A:H1299 B:HeLa S3 (anti-TYK2 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TYK2(anti-TYK2 antibody) antibody at 1:200 dilution.

 

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