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Home Antibody All anti-TUBB3 antibodies

Anti-TUBB3 TRUEMAB Antibody clone 5H2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500047
  • TUBB3 (beta III Tubulin) mouse monoclonal antibody, clone 5H2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416872) , 20ug
100ul 379 In Stock
CF500047
  • Carrier-free (BSA/glycerol-free) TUBB3 mouse monoclonal antibody, clone 5H2
100ug $450 3-4 weeks
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WB(2)
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Also for TUBB3 (NM_006086)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-150 of human TUBB3 (NP_006077) produced in E.coli.
Clone Nameclone 5H2 IsotypeIgG1
Species ReactivityHuman Concentration0.45mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:1000~2000,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tubulin, beta 3 class III (TUBB3), transcript variant 1
Alternative Namebeta-4; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; TUBB4
Database LinkNP_006077
FunctionTubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement, and the cytoskeleton. Except in the simplest eukaryotes, tubulin exists in all cells as a mixture of similar, but not identical, sets of alpha and beta tubulin polypeptides. Within either set of polypeptides, individual subunits diverge from each other (both within and across species) at less than 10% of the amino acid positions. The most extreme diversity is localized to the 15 residues of the carboxy terminal. For beta tubulin five evolutionarily conserved isotype clones have been identified. These are almost totally conserved in the subunits utilized in the same cell types of different species, with the exception of the hematopoietic beta tubulin which is the most highly divergent in sequence and is not conserved between species. Research has been centered around the hypothesis that these beta tubulin isotypes contribute to unique functional properties. It has been reported that the different isotypes of tubulin differ from each other in their ability to polymerize into microtubules.
Related Pathway
Cell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TUBB3 (RC200755, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TUBB3.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TUBB3 monoclonal antibody.

 

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