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Home Antibody All anti-TTR antibodies

Anti-TTR Antibody EPR3219

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SKU Description Amount Price Availability*  
TA301337
  • Rabbit Monoclonal Antibody against TTR (Clone EPR3219)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400134) , 20ug Explanation
100ul $325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Prealbumin was used as an immunogen.
Clone NameEPR3219 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000~5000; IHC: 1: 100~250; FC: 1:80
Predicted MW Explanation 16 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens transthyretin (TTR)
Alternative NameCTS; CTS1; HEL111; HsT2651; PALB; TBPA
Database LinkNP_000362
Entrez Gene 7276 Human
FunctionPrealbumin (TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF). It is reported to be either selectively transported across or synthesized within the blood-CSF barrier (3). Over 80 different disease-causing mutations in prealbumin have been reported. The vast majority is inherited in an autosomal dominant manner and is related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. A small portion of prealbumin mutations are apparently non-amyloidogenic (4). The human amyloid disorders, familial amyloid polyneuropathy, familial amyloid cardiomyopathy and senile systemic amyloidosis, are caused by insoluble prealbumin fibrils (2).
Related PathwaySecreted ProteinES Cell Differentiation/IPS

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Prealbumin antibody; All lanes : Anti-Prealbumin antibody [EPR3219] at 1/1000 dilution.Lane 1 : Human plasma lysate.Lane 2 : Human placenta lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 16 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Prealbumin antibody [EPR3219]; TA301337, at a 1/100 dilution, staining Prealbumin in paraffin embedded Human liver tissue by Immunohistochemistry.
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