Home Antibody All anti-TSPO antibodies
Also for TSPO (NM_000714)
|Synthetic peptide surrounding amino acid 81 of mouse PBR|
|Human, mouse, rat
||WB: 0.5-4ug/ml, IHC: 10-20ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit anti-PBR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2.|
|Homo sapiens translocator protein (18kDa) (TSPO), transcript variant PBR|
|BPBS; BZRP; DBI; IBP; MBR; mDRC; PBR; PBS; pk18; PKBS; PTBR|
Entrez Gene 706 Human
Entrez Gene 12257 Mouse
Entrez Gene 24230 Rat
|PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34 kDa voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis. |
|TransmembraneDruggable Genome Neuroactive ligand-receptor interaction|
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Western blot analysis of PBR expression in rat kidney tissue lysate.