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Home Antibody All anti-TSLP antibodies

Anti-TSLP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306385
  • Rabbit Polyclonal TSLP Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409755) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for TSLP (NM_033035)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTSLP antibody was raised against a 19 amino acid peptide from near the center of human TSLP.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens thymic stromal lymphopoietin (TSLP), transcript variant 1
Alternative Namethymic stromal lymphopoietin
Database LinkNP_149024
Entrez Gene 85480 Human
Entrez Gene 53603 Mouse
FunctionThymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. At least two differentially spliced isoforms of TSLP are known to exist.
Related PathwayDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TSLP in A-20 cell lysate with TSLP antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
IHC Image
Immunohistochemistry of TSLP in human brain tissue with TSLP antibody at 2.5 ug/ml.

 

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