Home Antibody All anti-TRIM21 antibodies
Also for TRIM21 (NM_003141)
|Recombinant fragment corresponding to a region within amino acids 254 and 475 of SSA1 (Uniprot ID#P19474)|
|Human (Predicted: Pig, Bovine)
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Pig (81%), Bovine (82%)
|Homo sapiens tripartite motif containing 21 (TRIM21)|
|RNF81; Ro/SSA; RO52; SSA; SSA1|
Entrez Gene 6737 Human
|This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq]|
|Druggable Genome Systemic lupus erythematosus|
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Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308743 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded DLD-1 xenograft , using SSA1(TA308743) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using SSA1(TA308743) antibody at 1:200 dilution.