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Home Antibody All anti-TRAM2 antibodies

Anti-TRAM2 Antibody EPR2658

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310903
  • Rabbit Monoclonal antibody against TRAM2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415841) , 20ug
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TRAM2 was used as an immunogen.
Clone NameEPR2658 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens translocation associated membrane protein 2 (TRAM2)
Alternative NameKIAA0057
Database LinkNP_036420
FunctionTRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane (1). It facilitates proper folding of type I collagen (2). TRAM2 couples the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling increases the local Ca2+ concentration at the site of collagen folding (3).
Related Pathway

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WB Image
Western blot - TRAM2 antibody [EPR2658]; All lanes : Anti-TRAM2 antibody [EPR2658] at 1/10000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : PC-3 cell lysate.Lane 3 : MCF-7 cell lysate.Lane 4 : BxPC-3 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 43 kDa.

 

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