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Home Antibody All anti-TRAF3IP2 antibodies

Anti-TRAF3IP2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306088 Rabbit Polyclonal CIKS Antibody 100ug $325 3-7 Days
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Also for TRAF3IP2 (NM_001164281)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody

OriGene Data

ImmunogenCIKS antibody was raised against a synthetic peptide corresponding to amino acids 2 to 15 of human CIKS .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 3
Alternative NameACT1; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; PSORS13
Database LinkNP_001157753
Entrez Gene 10758 Human
FunctionNuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB associates with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappaB activator 1) (1,2). CIKS directly interacts with IKKgamma. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CIKS expression in human lung (lane A) and placenta (lane B) tissue lysates with CIKS antibody at 1 ug /ml.

IHC Image
Immunohistochemistry of CIKS in human lung tissue with CIKS antibody at 5 ug/ml.

IF Image
Immunofluorescence of CIKS in human lung tissue with CIKS antibody at 20 ug/mL.


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