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Anti-TPT1 Antibody Polyclonal


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Polyclonal TPT1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401136) , 20ug Explanation
100ug $325 3-7 Days
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OriGene Data

ImmunogenRabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC, IF
Predicted MW Explanation 19 kDa
BufferTPT1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TPT1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tumor protein, translationally-controlled 1 (TPT1), transcript variant 2
Alternative NameHRF; p02; p23; TCTP
Database LinkNP_003286
Entrez Gene 7178 Human
Entrez Gene 22070 Mouse
Entrez Gene 116646 Rat
FunctionTPT1 Antibody: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer’s disease and Down syndrome.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TPT1 in human brain tissue lysate with TPT1 antibody at (A) 0.5 and (B) 1 ug/mL.


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