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Home Antibody All anti-TPPP antibodies

Anti-TPPP Antibody EPR3315

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307136
  • Rabbit monoclonal antibody against TPPP(clone EPR3315)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416249) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for TPPP (NM_007030)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TPPP was used as an immunogen.
Clone NameEPR3315 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or ICC.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or ICC.

Reference Data

Target NameHomo sapiens tubulin polymerization promoting protein (TPPP)
Alternative Namep24; p25; p25alpha; TPPP/p25; TPPP1
Database LinkNP_008961
Entrez Gene 11076 Human
FunctionTubulin polymerization-promoting protein (TPPP) is an unfolded brain-specific protein that interacts with the tubulin/microtubule system, and is enriched in human pathological brain inclusions (1). TPPP can induce aggregation of alpha-synuclein, and can accumulate in oligodendroglial cell bodies containing fibrillized alpha-synuclein multiple system atrophy (MSA), a neurodegenerative disease. TPPP is a constituent of myelin and a high-affinity ligand for myelin basic protein (MBP), and has been shown to colocalize with MBP in myelin in normal human brains (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315]; All lanes : Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 23 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315]; TA307136 at 1/100 dilution staining Tubulin Polymerization Promoting Protein in Paraffin-embedded Human astrocytoma tissue by Immunohistochemistry.

 

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