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Home Antibody All anti-TPO antibodies

Anti-TPO Antibody EPR5379

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310902
  • Rabbit Monoclonal antibody against TPO
100ul $325 3-7 Days
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WB(1)
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Also for TPO (NM_000547)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain in human TPO was used as an immunogen.
Clone NameEPR5379 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC-P.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P.

Reference Data

Target NameHomo sapiens thyroid peroxidase (TPO), transcript variant 1
Alternative NameMSA; TDH2A; TPX
Database LinkNP_000538
FunctionTPO is a membrane-bound glycoprotein. It acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in TPO are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA (1).
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Thyroid Peroxidase antibody [EPR5379]; Anti-Thyroid Peroxidase antibody [EPR5379] at 1/1000 dilution + Human thyroid lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 103 kDa.

 

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