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Home Antibody All anti-TPM1 antibodies

Anti-TPM1 Antibody EPR5158

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311096
  • Rabbit Monoclonal antibody against Tropomyosin-1 (TPM1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424765) , 20ug
100ul $325 In Stock
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WB(1)
IHC(3)
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Also for TPM1 (NM_000366)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Tropomyosin-1 was used as an immunogen.
Clone NameEPR5158 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:500 - 1:1000; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 5
Alternative NameC15orf13; CMD1Y; CMH3; HTM-alpha; LVNC9; TMSA
Database LinkNP_000357
FunctionTropomyosin-1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. Tropomyosin-1 is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. Mutations in Tropomyosin-1 are associated with type 3 familial hypertrophic cardiomyopathy (1).
Related Pathway

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WB Image
Western blot - Tropomyosin 1 (alpha) antibody [EPR5158]; All lanes : Anti-Tropomyosin 1 (alpha) antibody [EPR5158] at 1/1000 dilution.Lane 1 : Human heart lysate.Lane 2 : Human skeletal muscle lysate.Lane 3 : HT-1080 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 33 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Tropomyosin 1 (alpha) antibody [EPR5158]; Immunohistochemical analysis of paraffin-embedded Human heart muscle tissue using TA311096 at 1/500
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Tropomyosin 1 (alpha) antibody [EPR5158]; Immunohistochemical analysis of paraffin-embedded Human skeletal muscle tissue using TA311096 at 1/500
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Tropomyosin 1 (alpha) antibody [EPR5158]; Immunohistochemical analysis of paraffin-embedded Human smooth muscle tissue using TA311096 at 1/500

 

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