Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
UltraMAB™ Antibodies - Validated with 10K Protein Chip
Immunohistochemical staining of paraffin-embedded Human normal colon tissue and colonrectal cancer tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
Immunohistochemical staining of paraffin-embedded Human normal lung tissue and lung adenocarcinoma tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
Immunohistochemical staining of paraffin-embedded Human normal ovary tissue and ovary cancer tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
Immunohistochemical staining of paraffin-embedded Human normal breast tissue and breast adenocarcinoma tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008].
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Immunohistochemical staining of paraffin-embedded Human normal colon tissue and colonrectal cancer tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
Immunohistochemical staining of paraffin-embedded Human normal lung tissue and lung adenocarcinoma tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
Immunohistochemical staining of paraffin-embedded Human normal ovary tissue and ovary cancer tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
Immunohistochemical staining of paraffin-embedded Human normal breast tissue and breast adenocarcinoma tissue using anti-TP53 mouse monoclonal antibody. (UM500049)
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