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Home Antibody All anti-TNNT2 antibodies

Anti-TNNT2 Antibody EPR3695

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307717
  • Rabbit monoclonal antibody against TNNT2 (clone EPR3695 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400130) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for TNNT2 (NM_000364)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Troponin T type 2 was used as an immunogen.
Clone NameEPR3695 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC: 1:100 - 250, IP: 1:10, WB: 1:100,000 - 500,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 1
Alternative NameCMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Database LinkNP_000355
FunctionThe troponin complex is located on the thin filament of striated muscle and is composed of three component polypeptides: troponin T (TNNT1; TNNT2), troponin I (TNNI1; TNNI2; TNNI3), and troponin C (TNNC) (1). Troponin T type 2 (TNNT2) is a cardiac troponin T isoform expressed in the human heart, that is essential for calcium-regulated myofibrillar ATPase activity (2). Troponin T (TnT) anchors the complex to the thin filaments in vertebrate striated muscle, and functions as a regulatory system for muscle contraction in response to changes to intracellular calcium ion concentration (3). All subunits of Tnnt2 have been associated with hypertrophic cardiomyopathy (HCM) (4).
Related Pathway

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WB Image
Western blot - Cardiac Troponin T antibody [EPR3695]; All lanes : Anti-Cardiac Troponin T antibody [EPR3695] at 1/100000 dilution.Lane 1 : Human heart lysate.Lane 2 : Human skeletal muscle lysate.Lane 3 : Human heart lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/1000 dilution.Predicted band size : 36 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cardiac Troponin T antibody [EPR3695]; TA307717 at 1/100 dilution, staining Cardiac Troponin T in paraffin embedded Human cardiac muscle tissue

 

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