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Home Antibody All anti-TNNT2 antibodies

Anti-TNNT2 Antibody EPR3695

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307717
  • Rabbit monoclonal antibody against TNNT2 (clone EPR3695 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400130) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for TNNT2 (NM_000364)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Troponin T type 2 was used as an immunogen.
Clone NameEPR3695 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC: 1:100 - 250, IP: 1:10, WB: 1:100,000 - 500,000,
Predicted MW Explanation 36 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 1
Alternative NameCMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Database LinkNP_000355
Entrez Gene 7139 Human
FunctionThe troponin complex is located on the thin filament of striated muscle and is composed of three component polypeptides: troponin T (TNNT1; TNNT2), troponin I (TNNI1; TNNI2; TNNI3), and troponin C (TNNC) (1). Troponin T type 2 (TNNT2) is a cardiac troponin T isoform expressed in the human heart, that is essential for calcium-regulated myofibrillar ATPase activity (2). Troponin T (TnT) anchors the complex to the thin filaments in vertebrate striated muscle, and functions as a regulatory system for muscle contraction in response to changes to intracellular calcium ion concentration (3). All subunits of Tnnt2 have been associated with hypertrophic cardiomyopathy (HCM) (4).
Related PathwayDruggable Genome Cardiac muscle contractionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Cardiac Troponin T antibody [EPR3695]; All lanes : Anti-Cardiac Troponin T antibody [EPR3695] at 1/100000 dilution.Lane 1 : Human heart lysate.Lane 2 : Human skeletal muscle lysate.Lane 3 : Human heart lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/1000 dilution.Predicted band size : 36 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cardiac Troponin T antibody [EPR3695]; TA307717 at 1/100 dilution, staining Cardiac Troponin T in paraffin embedded Human cardiac muscle tissue

 

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