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Home Antibody All anti-TNFSF4 antibodies

Anti-TNFSF4 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319731 Rabbit Polyclonal TNFSF4 Antibody 100ug $325 3-7 Days
LC401143 TNFSF4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for TNFSF4 (NM_003326)
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OriGene Data

ImmunogenRabbit polyclonal TNFSF4 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC, IF
Predicted MW Explanation 20 kDa
BufferTNFSF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TNFSF4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4), transcript variant 1
Alternative NameCD134L; CD252; GP34; OX-40L; OX4OL; TXGP1
Database LinkNP_003317
Entrez Gene 7292 Human
Entrez Gene 22164 Mouse
Entrez Gene 89814 Rat
FunctionTNFSF4 Antibody: The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNγ. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TNFSF4 in rat spleen tissue lysate with TNFSF4 antibody at (A) 0.5 and (B) 1 ug/mL


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