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Home Antibody All anti-TNFSF4 antibodies

Anti-TNFSF4 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319731
  • Rabbit Polyclonal TNFSF4 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401143) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for TNFSF4 (NM_003326)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRabbit polyclonal TNFSF4 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC, IF
BufferTNFSF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TNFSF4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4)
Alternative NameCD134L; CD252; GP34; OX-40L; OX4OL; TXGP1
Database LinkNP_003317
FunctionTNFSF4 Antibody: The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNγ. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Related Pathway
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of TNFSF4 in rat spleen tissue lysate with TNFSF4 antibody at (A) 0.5 and (B) 1 ug/mL

 

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