Home Antibody All anti-TNFSF15 antibodies
Anti-TNFSF15 Antibody Polyclonal
Also for TNFSF15 (NM_005118)
|TL1A antibody was raised against a peptide corresponding to 14 amino acids near the N terminus of human TL1A.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 2 ug/ml
|TL1A Antibody is supplied in PBS containing 0.02% sodium azide.|
|TL1A Antibody is Ion exchange chromatography purified.
|Homo sapiens tumor necrosis factor (ligand) superfamily, member 15 (TNFSF15), transcript variant 1|
|TL1; TL1A; VEGI; VEGI192A|
|TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-κB activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI).|
Cytokine-cytokine receptor interaction
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Western blot analysis of TL1A in PC-3 cell lysates with TL1A antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.