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Home Antibody All anti-TNFSF13B antibodies

Anti-TNFSF13B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306021
  • Rabbit Polyclonal BAFF Antibody
100ug 325 In Stock
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WB(1)
IF(1)
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Also for TNFSF13B (NM_001145645)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenBAFF antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human BAFF.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B), transcript variant 2
Alternative NameBAFF; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; ZTNF4
Database LinkNP_001139117
Entrez Gene 10673 Human
Entrez Gene 24099 Mouse
Entrez Gene 498666 Rat
FunctionMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kappaB and c-jun N-terminal Kinase) (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R (5,6). BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis (5).
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of BAFF in human HL60 cell lysate (H) and mouse spleen tissue lysate (M) with BAFF antibody at 1 ug/mL.
IF Image
Immunocytochemistry of BAFF in HL60 cells with BAFF antibody at 1 ug/mL.

 

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