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Home Antibody All anti-TNFSF13B antibodies

Anti-TNFSF13B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306021
  • Rabbit Polyclonal BAFF Antibody
100ug 325 In Stock
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WB(1)
IF(1)
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Also for TNFSF13B (NM_001145645)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenBAFF antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human BAFF.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B), transcript variant 2
Alternative NameBAFF; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; ZTNF4
Database LinkNP_001139117
FunctionMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kappaB and c-jun N-terminal Kinase) (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R (5,6). BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis (5).
Related Pathway
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of BAFF in human HL60 cell lysate (H) and mouse spleen tissue lysate (M) with BAFF antibody at 1 ug/mL.
IF Image
Immunocytochemistry of BAFF in HL60 cells with BAFF antibody at 1 ug/mL.

 

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