Home Antibody All anti-TNFSF13B antibodies
Also for TNFSF13B (NM_001145645)
|BAFF antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human BAFF.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||ELISA, WB: 1 ug/ml, ICC: 1 ug/ml
|PBS containing 0.02% sodium azide.|
|Ion exchange chromatography purified (Protein A or G Sepharose)
|Homo sapiens tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B), transcript variant 2|
|BAFF; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; ZTNF4|
|Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kappaB and c-jun N-terminal Kinase) (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R (5,6). BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis (5).|
Cytokine-cytokine receptor interaction
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of BAFF in human HL60 cell lysate (H) and mouse spleen tissue lysate (M) with BAFF antibody at 1 ug/mL.
Immunocytochemistry of BAFF in HL60 cells with BAFF antibody at 1 ug/mL.