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Home Antibody All anti-TNFRSF1B antibodies

Anti-TNFRSF1B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321270
  • Anti-TNFRSF1B Rabbit Polyclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400436) , 20ug
100ul $325 2-3 Weeks
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WB(1)
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Also for TNFRSF1B (NM_001066)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 291-461 amino acids of human tumor necrosis factor receptor superfamily, member 1B
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.3mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:1000-2000, WB: 1:200-1000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B)
Alternative NameCD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80
Database LinkNP_001057
FunctionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins; c-IAP1 and c-IAP2; which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown; however; c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2; which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Related Pathway
Apoptosis
Cytokine-cytokine receptor interaction

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WB Image
Predicted band size: 48 kDa . Positive control: Human colon cancer lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds)

 

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