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Home Antibody All anti-TNFRSF1A antibodies

Anti-TNFRSF1A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326458
  • Rabbit Polyclonal Anti-TNF-R1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400435) , 20ug
100µg 325 3-7 Days
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Also for TNFRSF1A (NM_001065)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide corresponding to AA 20-43 of the mouse TNF-R1 sequence, identical to rat and human over those residues
Clone Name IsotypeN/A
Species ReactivityHuman, Mouse, Rat, Monkey, Bovine, Canine, Rabbit Concentration1mg/ml
Guaranteed Application * Suggested DilutionsWB: 1:1000
BufferPBS pH 7.4; 50% glycerol, 0.09% azide.
Purification Peptide Affinity Purified
Note Identifies a band ~55kD on WB

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
Alternative NameCD120a; FPF; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55;
Database LinkNP_001056
FunctionThe Tumor Necrosis Factor Receptor (TNFR) also known as Cluster of differentiation (CD120) is a protein that belongs to the (TNF)/ (TNFR) superfamily. TNF interacts with two distinct receptors TNFR1 and TNFR2. These receptors share no homology on their cytoplasmic sequences.TNFR1 also known as p55/p60 is a high affinity receptor for TNF-. The TNFR1 has an extracellular domain with variable numbers of cysteine-rich repeats. The functional properties of TNFR1 are targets in new therapies for osteoporosis, chronic inflammatory and autoimmune diseases . The TNF-/TNFR1 receptor complex is responsible for the recruitment and the subsequent activation of the caspase (aspartate-specific cysteine proteases) that regulate apoptosis.
Related Pathway
Apoptosis
Cytokine-cytokine receptor interaction
MAPK signaling pathway

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