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Home Antibody All anti-TNFRSF1A antibodies

Anti-TNFRSF1A Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA326458 Rabbit Polyclonal Anti-TNF-R1 Antibody 100µg $325 3-7 Days
LC400435 TNFRSF1A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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Also for TNFRSF1A (NM_001065)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenPeptide corresponding to AA 20-43 of the mouse TNF-R1 sequence, identical to rat and human over those residues
Clone Name IsotypeN/A
Species ReactivityHuman, Mouse, Rat, Monkey, Bovine, Canine, Rabbit Concentration1mg/ml
Guaranteed Application * Suggested DilutionsWB: 1:1000
BufferPBS pH 7.4; 50% glycerol, 0.09% azide.
Purification Peptide Affinity Purified
Note Identifies a band ~55kD on WB

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
Alternative NameCD120a; FPF; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55;
Database LinkNP_001056
Entrez Gene 7132 Human
Entrez Gene 21937 Mouse
Entrez Gene 25625 Rat
Entrez Gene 722033 Monkey
FunctionThe Tumor Necrosis Factor Receptor (TNFR) also known as Cluster of differentiation (CD120) is a protein that belongs to the (TNF)/ (TNFR) superfamily. TNF interacts with two distinct receptors TNFR1 and TNFR2. These receptors share no homology on their cytoplasmic sequences.TNFR1 also known as p55/p60 is a high affinity receptor for TNF-. The TNFR1 has an extracellular domain with variable numbers of cysteine-rich repeats. The functional properties of TNFR1 are targets in new therapies for osteoporosis, chronic inflammatory and autoimmune diseases . The TNF-/TNFR1 receptor complex is responsible for the recruitment and the subsequent activation of the caspase (aspartate-specific cysteine proteases) that regulate apoptosis.
Related PathwaySecreted ProteinTransmembraneTranscription FactorsDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionApoptosisAdipocytokine signaling pathwayAlzheimer's diseaseAmyotrophic lateral sclerosis (ALS)More Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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