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Home Antibody All anti-TNFRSF14 antibodies

Anti-TNFRSF14 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306307
  • Rabbit Polyclonal TNFRSF14 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401254) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for TNFRSF14 (NM_003820)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTNFRSF14 antibody was raised against a 15 amino acid peptide from near the amino terminus of human TNFRSF14.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 14 (TNFRSF14), transcript variant 1
Alternative NameATAR; CD270; HVEA; HVEM; LIGHTR; TR2
Database LinkNP_003811
FunctionTumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappaB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.
Related Pathway
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of TNFRSF14 in mouse thymus tissue lysate with TNFRSF14 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of TNFRSF14 in mouse thymus tissue with TNFRSF14 antibody at 1 ug/ml.

 

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